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How to cite this article: Narayanan A, Somasundaram A. Trichoepithelioma. CosmoDerma 2021;1:23.
A 52-year-old man presented with multiple, skin-colored to hyperpigmented, smooth surfaced, firm, papules, and nodules of size varying from 2 to 8 mm over the periocular area, perioral area, dorsum of nose, and bilateral nasolabial folds [Figure 1]. His daughter had fewer and smaller, but similar, lesions on her face. Based on the clinical morphology, family history and histopathological findings, a diagnosis of trichoepithelioma was made. Trichoepithelioma is a benign appendageal proliferation of cells of follicular germinative differentiation. The familial variant is inherited in an autosomal dominant pattern with decreased expression and penetrance in males.
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- Clin Exp Dermatol. 2020;45:508-11.A novel nonsense mutation of the CYLD gene in a Turkish family with multiple familial trichoepithelioma.
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