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How to cite this article: Narayanan A, Rajesh NG, Thappa DM. Sebaceoma. CosmoDerma 2021;1:15.
A 50-year-old male patient presented with a history of a small, yellowish papule on the right temporal scalp persisting for 5 years. He had undergone an excision biopsy which was reported as squamous cell carcinoma in a private histopathology lab. The patient brought the histopathology block and slide sections to us for second opinion. The slide was reviewed at our hospital with a differential diagnosis of squamous cell carcinoma and benign appendageal tumor. Histopathological examination revealed a well-circumscribed nodule arising from epidermis composed of mature sebocytes with abundant clear cytoplasm and central round nucleus. These sebocytes were admixed with basaloid cells [Figure 1a and b]. There was no evidence of mitosis, dysplasia, or necrosis [Figure 2a and b]. A diagnosis of sebaceoma was made based on the histopathological findings and the patient was reassured regarding the benign nature of the lesion. Sebaceoma usually presents as a deep nodule in the head-and-neck area. The nodule is not clinically distinctive except for a yellow color and requires histopathological examination for confirming the diagnosis. Often, complete excision of sebaceoma is required to exclude the possibility of basal cell carcinoma with sebaceous differentiation.
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Conflicts of interest
Devinder Mohan Thappa is the Editor-In-Chief of the journal.