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Pseudoxanthoma elasticum and angioid streaks
How to cite this article: Ramamoorthy L, Rout N, Kaur A. Pseudoxanthoma elasticum and angioid streaks. CosmoDerma 2023;3:135.
A 33-year-old male known case of pseudoxanthoma elasticum complained of increased skin lesions over the neck and axilla for the past 3 years. There was no family history of similar complaints. Cutaneous examination showed multiple, discrete-to-confluent, yellowish, flat-topped papules with a cobblestone-like appearance distributed symmetrically over the neck and bilateral axilla [Figure 1]. The rest of the physical examination was found to be normal. Ocular examination on fundoscopy showed a peau d’orange appearance, comet tail lesions, and angioid streaks [Figure 2].
Angioid streaks are the most common eye findings in pseudoxanthoma elasticum and have been reported in 59–87% of the cases. They are asymptomatic, but when it extends into the foveola, it leads to loss of visual acuity. It can also cause irreversible vision loss due to rupture of the Bruch’s membrane, subretinal hemorrhages, and macular neovascularization. This case highlights that ophthalmological examination is essential for patients without ocular symptoms and counseling about systemic complications and regular follow-up.
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