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Cutis verticis gyrata, leonine facies, and nail clubbing: A clue to pachydermoperiostosis

*Corresponding author: Chandra Sekhar Sirka, Department of Dermatology and Venereology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India. csirka2006@gmail.com
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Accepted: ,
How to cite this article: Gupta P, Sangwan P, Sirka C. Cutis verticis gyrata, leonine facies, and nail clubbing: A clue to pachydermoperiostosis. CosmoDerma. 2026;6:18. doi: 10.25259/CSDM_216_2025
Cutis verticis gyrata classified as primary (without associated feature) or secondary (pachydermoperiostosis, acromegaly, cerebral tumors, aneurysm, Noonan syndrome, etc.)[1] A 22-year-old male presented with 9-year duration of multiple skin folds over scalp [Figure 1a], increased seborrhea over face [Figure 1b], non-inflammatory swelling of multiple joints, nail clubbing, and generalized hyperhidrosis. Normal insulin-like growth factor (IGF) levels favored the diagnosis of pachydermoperiostosis. Acromegaly was ruled out by the presence of clubbing, periostosis, normal IGF levels, and absence of jaw prognathism. Cutaneous manifestations disfavored the diagnosis of Paget’s disease. Genetic analysis was not performed in our case due to unaffordability.

- (a) Clinical image of the bald scalp showing longitudinal skin folds with thickening of the skin suggestive of cutis verticis gyrata. (b) Clinical image of the face showing coarse facies, increased skin folds, and sebaceous hyperplasia giving rise to leonine facies.
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The authors certify that they have obtained all appropriate patient consent forms. In the form, the patients have given their consent for their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Conflicts of interest:
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation:
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.
Financial support and sponsorship: Nil.
References
- Primary essential cutis verticis gyrata-case report. An Bras Dermatol. 2014;89:326-8.
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